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Description A straightforward way to master a complex subject! This bestselling textbook presents all the knowledge you need to get through your pharmacology course and beyond, using a clear and accessible approach that makes the material easy and interesting to learn. Progressing logically from a molecular understanding of receptors and drug actions to the clinical uses of the most important groups of drugs, it delivers the latest information on cannabinoids and rimonabant, Cox 2 inhibitors, pharmacogenetics, biopharmaceuticals, and drug abuse?as well as "lifestyle drugs" such as performance-enhancing substances, botulinum toxin, and Viagra?. And now, online access via STUDENT CONSULT makes it an even more effective learning resource!Audience Medical and Undergraduate students studying Pharmacology, Pharmacy students Contents Section 1. General Principles 1. What is pharmacology? 2. How drugs act: general principles3. How drugs act: molecular aspects 4. Cellular mechanisms: excitation, contraction and secretion 5. Cellular mechanisms: cell proliferation and apoptosis 6. Method and measurement in pharmacology7. Absorption and distribution of drugs 8. Drug elimination and pharmacokinetics Section 2. Chemical Mediators 9. Chemical mediators and the autonomic nervous system 10. Cholinergic transmission11. Noradrenergic transmission 12. Other peripheral mediators: 5-hydroxytryptamine and purines 13. Peptides and proteins as mediators14. Nitric oxide 15. Local hormones, inflammation and immune reactions 16. Anti-inflammatory and immunosuppressant drugs Section 3. Drugs Affecting Major Organ Systems 17. The heart18. The vascular system19. Atherosclerosis and lipoprotein metabolism20. Haemostasis and thrombosis21. The heamopoietic system 22. The respiratory system 23. The kidney 24. The gastrointestinal tract25. The endocrine pancreas and the control of blood glucose 26. Obesity 27. The pituitary and adrenal cortex28. The thyroid 29. The reproductive system30. Bone metabolism Section 4. The Nervous System 31. Chemical transmission and drug action in the central nervous system 32. Amino acid transmitters33. Other transmitters and modulators34. Neurodegenerative disorders 35. General anaesthetic agents 36. Anxiolytic and hypnotic drugs 37. Antipsychotic drugs 38. Drugs used in affective disorders39. Antiepileptic drugs 40. Analgesic drugs 41. CNS stimulants and psychotomimetic drugs42. Drug dependence and drug abuse43. Local anaesthetics Section 5. Drugs Used in the Treatment of Infections and Cancer 44. Basic principles of chemotherapy45. Antibacterial drugs 46. Antiviral drugs 48. Antiprotozoal drugs 49. Anthelminthic drugs 50. Cancer chemotherapy Section 6. Special Topics 51. Individual variation and drug interaction52. Unwanted effects and drug toxicity53. Lifestyle and non-medical uses of drugs53. Gene therapy 54. Drug discovery and developmentAppendix Index